Submandibular secretory organ is one of the major salivary secretory organs found in human existences. The others are sublingual and the parotid secretory organs. The three secretory organs are found to be located in the oral cavity and around the pharynx. All the three secretory organs together with other salivary secretory organs serve the intent of releasing spit in the oral cavity. The submandibular salivary secretory organ specifically secretes saliva under the lingua in the front part ( Yuasa et al 1997 ) . The chief causes of submandibular secretory organ obstructor are the salivary calculuss and they are known to do puffiness of the secretory organs several repeated times particularly during repasts. Saliva is besides produced by other group of secretory organs referred to as minor secretory organs ( Yuasa 1998 ) . These minor secretory organs are found in the oral cavity liners, lips and roof of the mouth. Sometimes they can be located in the olfactory organ. These glanses are susceptible to a figure of diseases and upsets some of which include swelling or balls besides known as obstructor or tumours ; infections by bacteriums, viruses and this can take to epidemic parotitiss ; dry oral cavity and hurts largely lacerations ( Rauch and Gorlin 1970 ) .
Submandibular secretory organ Anatomy.
The structural anatomy of submandibular secretory organ was studied earlier in the 17th century and was subsequently visualized in the 1990s by assistance of an endoscope. The endoscopic technological techniques have developed quickly sing the past 10 old ages and this has been accompanied by sialoendoscopy debut and an betterment in direct submandibular secretory organ diagnosing and geographic expedition. This has besides permitted minimum invasive interventions of surgery to acquire off with the obstructor.
Obstruction of submandibular secretory organs merely refers to interference with saliva flow in these secretory organs usually due to formation of rock in the secretory organs. The marks and symptoms of this upset usually occur when one is holding repasts. The individual enduring from this disease can originate production of the spit but the produced spit can non be able to come out through the ductal system taking to accretion in the several secretory organ. It is this accretion that leads to swelling of the secretory organ involved and this is followed by terrible hurting and the happening of an infection at this phase can put in ( Capaccio et al 2003 )
Causes of obstructor.
The chief cause of salivary secretory organ obstructor is the Sialolithiasis which accounts for about 60 six per centum of the entire secretory organ obstructor instances. Tumors, cauli rocks and stenosiss besides account for a comparatively high per centum of secretory organ obstructor. However obstructor is besides caused by other minor factors including stoppers of mucous secretion, neoplasm compaction, foreign organic structures and sometimes obstructor by granulation tissue which can be due excessively immunological jobs. Obstruction can besides be as a consequence of exposure of the secretory organ to the radioiodine therapy which causes harm to these secretory organs particularly for persons enduring from thyroid carcinoma ( Milton, Thomas and Bickerton 1986 ) . Obstruction of the salivary canal can besides be caused deficient coordination of neuromuscular masseteric. Finally obstructor can be due to traumatic dentitions eruption or initiation of dental plate compaction in the opening of the salivary canal.
Other possible causes submandibular salivary secretory organ obstructor.
There are several possible causes of obstruction or obstructor of the submandibular salivary secretory organs. These factors can either be classified as extraductal, ductal or intratuctal factors. Extraductal causes are besides termed as interductal causes which can happen due to force per unit area built up from the other tumours next or next to the submandibular secretory organ. The force per unit area built up in these next canals or tumours cause swelling of these canals. When these canals swell outwards, the submandibular secretory organs near to them acquire compressed taking to their obstruction or obstructor to flux of spit. Other than the force per unit area from the tumours adjacent to the submandibular secretory organs, other constructions of anatomy close to these secretory organs can besides do compaction force per unit area. Ductal factors or causes involve stenosiss of fibre that criss-cross in the interior of the canals of the submandibular secretory organs. These stenosiss emerge from the walls of the submandibular secretory organ canals and turn towards the hollow side doing obstructor or obstruction to flux of spit. Intraductal factors or causes include things like mucose stoppers or the concretion. Accretion of the mucose on the walls of the canals of submandibular secretory organs will finally take to decrease of the infinite available for flow of the spit. Elevated degrees of this mucose accretion lead to obstructor. The mucose is believed to be secreted by some enzymes in the walls of the canals.
In a instance where the rock does non blockade the canal of the secretory organ wholly, the secretory organ will merely demo the swelling consequence at a clip of feeding and so goes back to normal after the repasts but this state of affairs will once more reiterate in the following feeding session. The abnormally pulled spit is most likely to acquire septic and this leads to extra terrible hurting and secretory organ swelling. There is a likeliness of the secretory organ going abscessed if this status is left unattended to for a long clip ( Epker 1972 ) .
Abnormality is one of the causes of obstructor in some people. In instances where the major salivary secretory organs happen to hold some abnormalcies like development of bottlenecks, the spit may non be able to flux freely in such a instance and this can take to reduced flow of spit and this can make room for infections and other obstructor symptoms ( Becker et al 2000 ) .
The primary malignant and benign tumours of the salivary secretory organ usually appear as typical expansions or puffinesss of the affected secretory organs. In most instances tumours involves on one secretory organ and on really rare state of affairss will you tumours involve in more than one secretory organ ( Yoshimura et al 1989 ) . Tumors are detected as growing expansions in the submandibular country or in other countries like the parotid secretory organ, mouth floor, lips and besides in the cheeks. The major secretory organs ‘ malignant tumours are described as fast growth, can take to loss of gesture of the side of face which is affected either entirely or partially and these tumours are really painful. The probe of the symptoms needs to be carried out quickly ( Spiro 1998 ) .
The chief methods of diagnosing of any salivary secretory organ disease are by proving in the research lab, physical scrutiny and sometimes the history of an person is put in consideration. In a state of affairs where an person is suspected of holding a major salivary secretory organ obstructor, there will be need to anaesthetize the oral cavity salivary canal gap, investigation and distend it to enable the transition of the clogging rock. The usage of dental X raies may besides assist in location of the calcified rocks. A CT scan type of X ray will be helpful in instance a mass is located in the secretory organ and this type of scan will demo if the placed mass is portion of the secretory organ or a lymph node associate ( Bodner 2002 ) .
Salivary secretory organ diseases can be tackled by either medical intervention or by surgical operation. The method to be used for intervention will be determined by the nature of the secretory organ job. If the nature of the job is one that attacks the organic structure as a whole so this must be treated and may necessitate farther audiences from other specializers but if the status involves obstructor of the salivary secretory organs and other secretory organ infections so antibiotics can rectify the state of affairs. However some instances of secretory organ diseases may necessitate canal instrumentality. In the instance where a mass has developed in the salivary secretory organ, the mass remotion by surgery is necessary. When transporting out surgery, attention must be taken to avoid harm to the nervousnesss located in the secretory organs ( Drage 2002 ) .
Sialolithiasis/Calculi ( rocks )
In many instances, this upset occurs largely in the submandibular salivary secretory organs and canals. However a few instances are reported to happen in the parotid secretory organs. The chief cause of the stenosiss can be due to the injury that can originate from cheek biting. Other causes may be due to dental plates, concretion and sometimes post surgery effects. The persons enduring from this status experience several symptoms ( Marchal et al 2001 ) . They feel pain at the clip of feeding and this hurting is relentless and the swelling occurs largely during eating. The discharge of the spit and Pus from these secretory organs will alleviate these symptoms. Failure to go to to this status will take to stagnancy and accretion of the spit in the affected secretory organs taking to happening of infection. If this state of affairs continues for long without any attending so the patient ‘s secretory organs may be destructed for good ( Nahlieli et al 2000 ) . This upset can be treated or managed but the direction or intervention depends on the type, the location and the degree of devastation of the involved secretory organs. The intervention measures largely employed include canal repositioning, canal Reconstruction, calculus remotion by surgery, stenosis dilation and besides gland deletion ( Renhen 2001 ) .
The major secretory organs ‘ malignant tumours are described as fast growth, can take to loss of gesture of the side of face which is affected either entirely or partially and these tumours are really painful. The probe of the symptoms needs to be carried out quickly. The chief symptoms of this upset as described include hurting, weak facial nervousnesss, lump tethering and fast growing of the tumour. The sort of probes that can be employed in this instance can either by MRI scan or usage of CT scan. A all right needle cytological aspirate can be applicable but the job is that this probe is dearly-won taking to many concerns ( Brown 2002 ) .
Adenoid cystic carcinoma. This status is divided to three subtypes. There is the cannular type, the cribriform type and the solid type. Among these three types, the most aggressive is the solid type. These three subtypes of the adenoid cystic carcinoma may happen in the same tumour or individually in different tumours. The features, marks and symptoms include perineural invasions which occur in about 60 per centum of the patients ‘ diagnosed with this upset. There is besides cervical metastasis although this is rare and occurs merely in approximately eight to thirteen per centum of the patients while the other symptom is the distant metastasis which happens in about 50 per centum of the patients ‘ diagnosed with this disease and this is largely sited in the castanetss and the lungs ( Seaver 1979 ) . The most employed intervention or direction is adenoid cystic carcinoma surgery as the primary intervention. The other direction techniques include entire parotidectomy and this is largely done when there is suspension of tumour clinical invasion. Radiotherapy can besides be employed in instance surgery is non successful. Then there is a demand to make frequent follow ups Incas of extremely susceptible patients to this upset in order to pull off it ( Chummun 2001 )
Acinic cell carcinoma is normally located in the parotid secretory organ. This disease appears as a mass turning easy in the secretory organs and it is accompanied with hurting and tenderness. This tumour looks similar to cells of serous acinar. Other cases related to this status have been reported in the submandibular secretory organs and other salivary secretory organs. Persons with different age can endure from this disease but kids and average aged persons ( between 40s and 50s ) are most susceptible. This status can be treated or managed by using assorted surgery degrees followed radiation therapy. The other intervention method is neutron beam radiation, chemotherapy and besides conventional radiation ( Baruchin 2000 ) .
Mucoepidermoid carcinoma incidences happen most likely compared to other two types. Persons aged between 20 and 50 are the most susceptible. This status can happen in any salivary secretory organ but many such instances have been witnessed or apparent in the smaller salivary secretory organ of the roof of the mouth. This status can eat deep into the dentigerous cyst wall. Symptoms of both high and intermediate signifier of this status include metastasis to the part ‘s lymph. This status is treated or managed by surgical dissection. The other method of direction is the postoperative radiation therapy ( Medina 1998 ) .
Several disease conditions affect salivary secretory organs and they are brought about by different factors. All the medical applications that are employed in any status of this diseases will either be surgical or by usage of medical specialty. These sorts of interventions are done by sawboness with experience in the caput and neck subdivisions of the organic structure. These sawboness are referred to as otolaryngologist sawboness and in this instance they are specialized in both caput and cervix related surgeries. ( Koch et al 2005 ) . Many more establishments that offer unwritten surgery and any other related researches should be enhanced and accomplished to be able to minimise these conditions and be able to manage even much more complicated diseases related to salivary secretory organs.